#Unrealistic optimism regression trial#

Effective interventions to counteract unrealistic optimism may need to address the psychological factors that give rise to distorted risk/benefit processing.',

#Unrealistic optimism regression trial#

This sense of control may underlie unrealistic optimism about benefiting personally from trial participation. Conclusion Patient-subjects reported that they can, at least partially, control the benefits they receive from participating in an early-phase oncology trial. However, in multivariate regression analysis, awareness and mental image dropped out of the model and perceived controllability was the only factor independently associated with unrealistic optimism (p<0.0001). Two other risk attribute variables, awareness of indicators (p=0.024) and mental image (p=0.022), were correlated with unrealistic optimism. Perceptions of control were found to predict unrealistic optimism. Significant levels of perceived controllability were found with respect to all nine research-related questions. Results One hundred and seventy-one patient-subjects agreed to be interviewed for our study. Respondents completed questionnaires designed to assess unrealistic optimism and several risk attribute variables that have been found to evoke the bias in other contexts. Methods A study of patient-subjects enrolled in early-phase oncology trials was conducted at two sites in the USA. We expected perceptions of control to be a strong correlate of unrealistic optimism. Our aim was to investigate the cognitive and motivational factors that evoke this bias in this context. Effective interventions to counteract unrealistic optimism may need to address the psychological factors that give rise to distorted risk/benefit processing.Ībstract = 'Purpose Recent research has found unrealistic optimism (UO) among patient-subjects in early-phase oncology trials. Purpose Recent research has found unrealistic optimism (UO) among patient-subjects in early-phase oncology trials.